Showing posts with label surgery. Show all posts
Showing posts with label surgery. Show all posts

Tuesday, February 16, 2010

Robotic prostatectomy love affair driven by marketing


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Gina Kolata's NYT piece, "Results Unproven, Robotic Surgery Wins Converts," looks at how "robot-assisted prostate surgery has grown at a nearly unprecedented rate."

Excerpts from the story:

• "..robot-assisted prostate surgery costs more -- about $1,500 to $2,000 more per patient. And it is not clear whether its outcomes are better, worse or the same."


• "Meanwhile, marketing has moved into the breach, with hospitals and surgeons advertising their services with claims that make critics raise their eyebrows."

• "Medical researchers say the robot situation is emblematic of a more general issue. New technology has sometimes led to big advances, which can justify extra costs. But often, technology spreads long before investigators know whether it is worthwhile."

• "...a situation like robot-assisted surgery illustrates how patients may end up making what can be life-changing decisions based on little more than assertive marketing or the personal prejudices of their surgeon.

"There is no question there is a lot of marketing hype," said Dr. Gerald L. Andriole Jr., chief of urologic surgery at Washington University. Dr. Andriole does laparoscopic prostate surgery, and although he tried the robot, he went back to the old ways.

"I just think that in this particular instance, with this particular robot," he said, "there hasn't been a quantum leap in anything."

Wednesday, February 10, 2010

Abdominal surgery riskier for older adults

Abdominal surgery is carried out on two million older Americans every year. One factor that should be considered when proposing abdominal surgery is the increased risk of complications and mortality in the older patient after these operations. A team from the University of Washington School of Medicine, Seattle, has carried out a study of complications and death rates after abdominal surgery in a group of 101,318 adults aged 65 or more. The abdominal surgery included operations like gall bladder removal, hysterectomy and colectomy. They recorded complications occurring within 90 days of discharge from hospital and deaths occurring within 90 days of hospital admission.

The overall complication rate was 17.3% and the mortality rate was 5.4%. The risk of complications after abdominal surgery went up with age. Between 65 and 69 it was 14.6% but at age 90 or more it was 22.7%. A similar trend was found with mortality following abdominal surgery. It was 2.5% in the 65 to 69 age group but rose to 16.7% in those aged 90 or older. It may be that the stress of abdominal surgery is just so much greater for an older body. Therefore, doctor and patient must decide whether abdominal surgery is really necessary (of course, it may be essential for survival) and, if so, how post-operative complications may best be avoided.

Source:

Massarweh N et al Impact of advancing age on abdominal surgical outcomes Archives of Surgery December 2009;144:1108-1114

Checklists and Culture in Medicine

Surgeon and journalist, Atul Gawande, is getting quite a bit of deserved press and blog attention for his new book, The Checklist Manifesto: How to Get Things Right. The premise of his book is simple – checklists are an effective way to reduce error. But behind that simple message are some powerful ideas with significant implications for the culture of medicine.

One of the biggest ideas is that medicine has culture – a way of doing things and thinking about problems that subconsciously pervades the practice of medicine. This idea is not new to Gawande, but he puts it to powerful practice.

The Humble Checklist

Gawande tells not only the story of the checklist but of his personal experience designing and implementing a surgery checklist as part of a WHO project to reduce morbidity and mortality from surgery. He borrowed the idea from other industries, like aviation, that use checklists to operate complex machinery without forgetting to perform each little, but vitally important, step.

The surgery checklist includes things like making sure the patient received pre-op antibiotics, making sure that blood is on hand for emergency transfusions, and also making sure that every member of the surgical team knows everyone else’s name.

In those hospitals in which the checklist was enforced surgical complications decreased on average by more than a third. That is a significant reduction, and saved hundreds of lives. This kind of impact is akin to the introduction of sterile technique.

Checklists are effective, Gawande argues, because some systems in our civilization have become too complex for the human mind to master. We have essentially crafted a civilization that is beyond our ability to manage using just raw brain power. Further, the consequences of minor mental error can be catastrophic – forget to flip one switch on a jet bomber and the plane may crash, killing everyone aboard. Make a decimal point error in dosing a medication and the patient may die.

Checklists minimize the probability of these small but consequential errors occurring.

This much of the story has been told numerous times on countless blogs and interviews as Gawande is conducting his book tour.

But the really interesting stuff are the other concepts behind the checklist, especially those that have to do with the culture of medicine.

The Culture of Medicine

Culture can be a strange and powerful thing – bestowing upon individuals a suite of assumptions, morals, attitudes, and mental habits of which they may not even be aware. In my opinion the most powerful part of Gawande’s book is when he steps back to consider what the culture of medicine is and how it affects practice (of course, with particular focus on the checklist).

He observes that in medicine the problem of increasing complexity has been handled by increasing expertise and specialization. Mistakes are minimized by training and repetition – so that procedures and patient management become routine. There is something to be said for training and repetition, but Gawande argues that medicine is now too complex for this strategy to be adequately effective. It is a setup for failure.

Rather we need to take the approach that other industries have taken – assume individuals will fail, but create a system that will catch them – the checklist.

This approach works, but may rub some physicians the wrong way – those trained in the culture of individualism and personal prowess and responsibility (sometimes referred to within medical circles as the “cowboy” approach – a term meant to be a little derogatory, although simultaneously containing a measure of respect).

Here I think that Gawande may be a little biased by his surgical background, and I think he may underappreciate that each specialty within medicine has its own subculture. Coming from a specialty at the more nerdy and less cowboy end of the medical cultural spectrum, I find nothing threatening about the concept of checklists or similar safeguards.

I also think this culture is generational – my experience with younger doctors in training is that they readily, even eagerly, adopt systems that help them avoid mistakes. They never knew a day when medicine was not so horrifically complex and ever changing that physicians could not use some external help to aid their inadequate brains.

Discipline and the Rise of the Machines

Another aspect of medical culture that Gawande touches on is the broader culture of professionalism itself. He argues that most professions are built upon the ethics of selflessness, expertise, and trustworthiness. However, some professions include the additional ethic of discipline – an ethic that is perhaps lacking in medicine.

Discipline in this context means doing the right things in detail every time. People and cultures have varying ability to be rigidly disciplined, but in general humans lack the kind of discipline that would preclude even the occasional lapse. A checklist is an outside imposition of discipline – to shore up a specific human weakness.

Taking this concept one step further, I would add that discipline is something machines do very well. If you give a computer a set of instructions, you can count on it to perform those instructions millions of times without variation.

I recently discussed elsewhere that there will likely be an increasing role of expert systems in the practice of medicine. This includes things like systems for analyzing radiographic studies and highlighting potential pathology, checking for drug-drug interactions when new prescriptions are written, suggesting possible diagnoses to be considered, and, yes, running through checklists or algorithms of proper evidence-based management. This may be as simple as reminding a physician to consider prescribing cardiovascular prophylaxis to their 60 year old patient with hypertension (something which does not happen as often as it should).

The checklist is therefore just one of many similar interventions that can aid all health care providers in the practice of their profession. And the advent of computers will likely aid in the implementation of checklists, algorithms, reminder systems, and automatic cross-checks – all with the goal of minimizing error and optimizing the practice of medicine.

Conclusion

Science-based medicine has been incredibly successful in extending and improving human life. It is also, in some ways, a victim of its own success. We now have more knowledge than any single expert can hope to know. We have developed advanced medical technology that works wonders, but amplifies the consequences of even minor errors. And we have raised the bar of expectation and professionalism to dizzying heights.

Gawande’s book not only provides us with an additional tool to deal with this growing complexity, but he encourages the entire profession (and other professions) to step back and look at the culture(s) and systems of medicine – to examine and challenge our assumptions, assess our approach to problem solving, and reconfigure ourselves to move forward.

I would like to step back even further and observe that Gawande’s book represents the deepest strength of the medical culture – it is earnestly self reflective. Harriet Hall’s post from yesterday represents another example of this, reflecting on the need to optimize the human element of every patient interaction, in the face of advancing technical demands.

Meanwhile the overarching purpose of science-based medicine is to reflect upon the optimal relationship between science and the practice of medicine.

Senator Murtha Dies Following Gallbladder Surgery



First of all, condolences to the family of Senator John Murtha who died recently following complications of gallbladder surgery. My thoughts are also with the surgeon in Maryland who performed the laparoscopic cholecystectomy. The death of a patient following routine elective surgery represents every surgeon's worst nightmare. The fact that it happened to a prominent American politician just exacerbates the stress and despair that the surgeon is probably feeling right now.

But I wanted to respond to a clip I watched earlier today from ABC News. In the video, Diane Sawyer (I know, you're supposed to say the lovely Diane Sawyer) interviews the ABC medical correspondent Richard Bessler, MD (trained as a pediatrician) about the possible causes of Senator Murtha's unfortunate outcome. Based on his explanations, she may as well have asked a 1st year medical student. According to Dr Bessler:

"to do this surgery, to remove the gallbladder, you need to separate it from the large intestine.....what may have happened, there may have been a small nick in the large intestine"

Now, what I think Dr Bessler is describing is an entity called a cholecysto-colonic fistula, which is very rare. For one thing, there are no natural attachments between the gallbladder and the large intestine. Certainly in cases of acute inflammation it is possible that an abnormal adhesion may form between the colon and gallbladder but these adhesions are typically very flimsy and easily divided; development of an actual connection between gallbladder and colon only occurs in cases of chronic inflammation over years and years. The likelihood that Murtha died from an injury to the colon is extremely low, statistically.

Most likely, Senator Murtha developed some sort of bile leak, either from the cystic duct stump or an actual injury to the common bile duct itself. Uncontained bile leakage throughout the abdominal cavity can lead to peritonitis, systemic inflammatory response syndrome (SIRS) and subsequent multiple organ failure/death. If there was a bowel injury, the most common source would be either the duodenum (often adherent to the neck of the gallbladder during the acute phase) or else small bowel adherent to the abdominal wall down by the umbilical port site (in placing the intial port, one can sometimes unwittingly cut into intestine that is stuck to the abdominal wall). Injury to the hepatic flexure of the colon would be much lower on my differential of possible causes.

I'm irritated because these are obvious points I'm making (from a surgical perspective). And here we have ABC News relying on the "expert testimony" of a pediatrician who works for the CDC. Dr Bessler, bless his heart, is obviously trying. You can tell that he looked at a human atlas and saw that the colon seems to be pretty close to the gallbladder. But his hypothesis is detached from any semblance of statistical likelihood. Why didn't ABC News ask, I don't know, maybe a SURGEON what the likely causes of Murtha's demise were? Is that asking too much? I know the guy is good looking and seems to handle himself well in front of the camera, but doesn't a news organization as influential as ABC News have an obligation to get their basic facts straight?

On another note.....posting has obviously been light. Probably will stay that way. Busy work and a crawling baby force a guy to have to eliminate certain indulgements.
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